Naty's Guest House is set in the Cusco City Centre district of Cusco, 400 metres from Hatun Rumiyoc, 400 metres from Religious Art Museum and 500 metres from Holy Family Church. Among the facilities at this property are a 24-hour front desk and a shared kitchen, along with free WiFi throughout the property. The property is 1.8 km from Wanchaq Train station, and within 500 metres of the city centre.

At the bed and breakfast, units are fitted with a desk, a flat-screen TV, a private bathroom, bed linen and towels. All units feature private entrance. All units include a wardrobe.

There is a coffee shop on-site.

Sightseeing tours are available within easy reach of the property.

Popular points of interest near the bed and breakfast include San Blas Church, Santa Catalina Convent and Cathedral of Cusco. The nearest airport is Alejandro Velasco Astete International, 3 km from Naty's Guest House, and the property offers a paid airport shuttle service.